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Depo-Medrol For Cats – Cats.com

Depo-Medrol for cats is a long-acting steroid injection. It’s used for inflammatory, immune-mediated, or allergy-type circumstances. On this article, you’ll be taught what Depo-Medrol is, when it could be used, the uncomfortable side effects to observe for, and a few regularly requested questions.

Fast Overview: Depo-Medrol For Cats


Suspension for injection.

Prescription Required?:


Frequent Names:

Methylprednisolone acetate

Obtainable Dosages:

The Depo-Medrol suspension is available in 20mg/ml, 40mg/ml, and 80mg/ml concentrations. 40mg and 80mg are available 1ml bottle measurement. All three concentrations are available 5ml and 10ml bottle measurement.

Expiration Vary:

Contents of the vial ought to be used inside 12 weeks of the vial being punctured. Product ought to be saved at room temperature.

About Depo-Medrol For Cats

Depo-medrol for cats is injected moderately than given orally, making it long-lasting and simpler to manage.

Depo-Medrol is a model identify for the injectable steroid drug methylprednisolone acetate. It’s manufactured by Zoetis Animal Well being.

There are a few totally different sorts of steroids. Steroid hormones, like progesterone and testosterone, act as sign messengers within the physique. Anabolic steroids, akin to these utilized by skilled bodybuilders, are those who act to extend muscle and bone development.

Corticosteroids are a 3rd class of steroids. Corticosteroids are concerned in quite a lot of mechanisms throughout the physique, together with stress response, immune response, regulation of irritation, and others.

Once we use corticosteroids, it’s sometimes for anti-inflammatory exercise to assist scale back swelling and irritation within the physique. At greater doses, it suppresses the immune system, which generally is a good or dangerous factor, relying on the illness being handled.

Whereas much like different glucocorticoid steroids like prednisone or hydrocortisone, methylprednisolone is much stronger. It’s 4-5 instances stronger than hydrocortisone.

Methylprednisolone is available in oral tablets and a few injectable types, however the model Depo-Medrol solely refers to a long-acting injectable type of the drug.

Additionally Learn: The 8 Greatest Cat Nutritional vitamins And Dietary supplements

What Does Depo-Medrol Do For Cats?

Depo-Medrol is right for cats that don’t reply nicely to taking medicine orally.

Depo-Medrol is utilized in the identical sorts of conditions the place an oral steroid like prednisolone could also be used.

This most frequently consists of inflammatory circumstances, immune-mediated circumstances the place the immune system is overreacting to a stimulus and inflicting hurt to the physique, and within the case of allergic circumstances.

Particularly, this may increasingly embrace irritation secondary to a wound or an infection, an immune-mediated situation akin to those who trigger blood problems like low pink blood cells or platelets. It additionally consists of inflammatory allergy circumstances like atopic dermatitis, inflammatory bowel illness (IBD), or feline bronchial asthma. It is usually used for sure sorts of most cancers that reply to corticosteroid remedy, akin to lymphoma.

In a majority of circumstances, the desire for the kind of steroid shall be oral. Oral prednisolone in cats could be dosed very carefully. Doses could be adjusted within the case of undesirable uncomfortable side effects or when the dose might must be elevated to be efficient.

Cats are pretty notorious for rejecting oral medicine. They usually spit them out or drool excessively afterward. As a result of cats don’t like being given medication orally, cat house owners danger getting bitten or scratched when trying to do that at house.

It’s principally in these conditions that veterinarians attain for Depo-Medrol. Depo-Medrol for cats is injected, and a dose lasts for weeks or months.

Nevertheless, whereas this may increasingly appear very handy, methylprednisolone acetate’s efficiency and lengthy length of impact additionally carry the danger of extra important uncomfortable side effects. Due to this, it’s usually a final selection for a lot of vets when seeking to deal with a cat with steroids

Additionally Learn: Greatest Cat Meals For IBD

Facet Results Of Depo-Medrol For Cats

Uncomfortable side effects of Depo-Medrol can happen in cats, however they’re usually milder than they’re in canine.

Typically talking, when in comparison with canine, cats require greater doses of a steroid to perform the identical results. Nonetheless, noticeable uncomfortable side effects are a lot much less obvious in cats.

The exception is when steroids are used for an extended time frame. As a result of Depo-Medrol is at all times a stronger and longer-acting medicine in comparison with prednisolone, uncomfortable side effects are extra noticeable, extra regarding, and require extra cautious monitoring.

The uncomfortable side effects of any steroid embrace elevated thirst, urination, and urge for food. There are additionally digestive upset indicators, with diarrhea being the most typical in cats with the potential for vomiting or decreased urge for food. Whereas extra generally seen in canine, ulcers of the abdomen and higher digestive tract will also be a possible danger.

These are much less appreciated in cats, particularly within the quick time period. If these uncomfortable side effects present up, they often resolve when the steroid is discontinued with some extra supportive care generally wanted.

Nevertheless, with a Depo-Medrol injection, the sluggish absorption can result in results which will final for weeks to months and could be totally different for every cat. So even with only a single Depo-Medrol injection, we’ve to contemplate the long-term use results of steroids to look out for.

Different Dangers And Issues

cat pouncing

Depo-Medrol is just not applicable for all cats. A veterinarian will enable you resolve whether it is proper to your cat.

A potent long-acting steroid should be used cautiously with any lively bacterial or viral infections, particularly extreme infections. Oral steroids are sometimes given alongside antibiotics for sure sorts of infections. With Depo-Medrol being stronger and its full length in a feline affected person not totally predictable, this might have an effect on the immune system’s potential to combat an infection.

The most important dangers for cats utilizing Depo-Medrol are the event of diabetes mellitus and congestive coronary heart failure.

Using corticosteroids within the physique can result in a level of resistance to insulin, the hormone that’s wanted to move blood sugar from the bloodstream and into cells. This not often has penalties over the quick time period, however long run, this resistance can result in the complete growth of diabetes.

Cats who’re chubby or overweight and already at a better danger of creating diabetes, are on the highest danger of crossing this threshold if a Depo-Medrol injection is used. Lengthy-acting steroid use may also result in weight achieve.

Lengthy-acting steroid use can lead a cat with coronary heart illness to coronary heart failure. This occurs when fluid begins to construct up in or across the lungs and generally additionally across the coronary heart itself, in addition to the stomach.

These two important dangers of Depo-Medrol use have led many veterinarians to display cats for danger previous to beginning Depo-Medrol as a main remedy selection. This consists of checking blood sugar and the guts itself for abnormalities. That is achieved utilizing a blood take a look at, x-rays, or an ultrasound of the guts.

Depo-Medrol use ought to be averted in pregnant cats and used cautiously for lactating animals.

Interactions With Different Drugs And Overdoses

Veterinarian doctor vaccinating cat at a vet clinic

Steroids generally work together with different medication and must be used rigorously.

There are a lot of drugs that work together with steroid use, particularly long-acting steroids. Frequent ones embrace different immunosuppressant medication like cyclosporine, non-steroidal anti-inflammatory drugs (akin to meloxicam or robenacoxib), and sure diuretic medication like furosemide.

Whereas the usage of Depo-Medrol is averted in diabetic cats, its use will usually result in elevated insulin necessities to handle the situation.

If steroids are getting used for immunosuppression, vaccination ought to be rigorously thought of, That is very true for live-attenuated viral vaccines, as a result of the immune system might not reply correctly. The vaccine(s) for panleukopenia virus, herpesvirus, calicivirus, and Chlamydia could also be modified reside whereas vaccines for rabies and feline leukemia virus (FeLV) should not.

As a result of Depo-Medrol is given intramuscularly with a needle and syringe, some transient ache could also be current at your kitty’s injection website. Make sure that to contact your vet if noticeable soreness lasts for greater than 24 hours.

Overdoses with Depo-Medrol are unusual since this medicine is at all times administered by a licensed veterinarian in accordance with pointers and never given at house. Nevertheless, even with a suitable dose, uncomfortable side effects are attainable.

In case you are ever involved that your kitty might have developed uncomfortable side effects or toxicity after receiving Depo-Medrol, be sure to contact your veterinarian, the ASPCA Animal Poison Management Heart (1-888-426-4435), or Pet Poison Helpline (1-855-764-7661) instantly for additional recommendation.

Additionally Learn: Drug Poisoning In Cats: Causes, Signs, & Therapy

Depo-Medrol For Cats Dosage

The dosage of Depo-Medrol varies relying in your cat’s wants.

Depo-Medrol is FDA-approved for intramuscular injection use in cats.

The standard intramuscular (IM) dose vary for Depo-Medrol for cats is between 10 mg and 20 mg per cat. The dosage used will rely upon the situation being handled. There are totally different concentrations of Depo-Medrol out there, so the quantity of the injection in milliliters (ml) might differ relying on what focus your vet carries.

The aim of any steroid remedy is to make use of the bottom efficient dose and the longest intervals between doses that also management indicators of illness. It’s common for Depo-Medrol injections to be given each 4-6 weeks for persistent circumstances, or sooner if indicators of illness return.

Closing Ideas

Lengthy-term use of Depo-Medrol in cats carries sure dangers, which must be monitored carefully.

Depo-Medrol for cats is a potent long-acting steroid. It’s used for very comparable functions as different steroids like prednisolone, however due to its efficiency and length and danger for long-term uncomfortable side effects, is commonly restricted to make use of in circumstances the place a cat can’t be administered an oral medicine virtually or safely. Any cat dad or mum whose kitty is receiving a Depo-Medrol injection ought to pay attention to the attainable dangers and options to its use, if any.

Additionally Learn: 10 Refined Indicators Your Cat Could Be Sick

Continuously Requested Questions

What does Depo-Medrol do for cats?

Depo-Medrol is a long-acting steroid injection. It’s used extra usually in circumstances the place an oral steroid is just not protected or sensible to manage to a cat, particularly the place steroid remedy is required for an extended time frame.

Depo-Medrol for cats is utilized in circumstances of irritation, and immune-mediated illness to suppress the immune system from harming the physique, allergic ailments like atopic dermatitis or feline bronchial asthma, and in circumstances of some cancers, akin to lymphoma. 

How lengthy does a Depo-Medrol shot final in cats?

The onset of aid, anti-inflammatory impact, or immune-suppressing length of any Depo-Medrol injection will fluctuate from cat to cat. It’s labeled as an injection for intramuscular administration and its sluggish absorption can result in a length of weeks to even a few months in some sufferers.

To know the way lengthy a Depo-Medrol shot might final, indicators of illness return should be monitored for. Frequent intervals for Depo-Medrol injections could also be each 4-6 weeks for persistent circumstances, or sooner if indicators of illness return extra rapidly. 

What are the uncomfortable side effects of a steroid shot in a cat?

Cats usually don’t present a lot in the best way of short-term uncomfortable side effects from steroid use. Nevertheless, with long-acting injections like Depo-Medrol, uncomfortable side effects could be extra obvious and generally extra severe.

Extreme thirst, urination, urge for food, and weight achieve are all attainable, in addition to digestive upset results like diarrhea, vomiting, and a lower in urge for food.

Cats in danger for diabetes mellitus, particularly chubby or overweight cats could be at greater danger of a long-acting potent steroid inducing diabetes.

Cats who’ve, or who’re in danger for, an underlying coronary heart illness situation, akin to hypertrophic cardiomyopathy (HCM) could be put at greater danger of creating congestive coronary heart failure (CHF) from steroid use.

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